124393-08-4Relevant academic research and scientific papers
Aromatic and Azaaromatic Diselenides, Benzisoselenazolones and Related Compounds as Immunomodulators Active in Humans: Synthesis and Properties
Mlochowski, Jacek,Kloc, Krystian,Syper, Ludwik,Inglot, Anna D.,Piasecki, Egbert
, p. 1239 - 1244 (2007/10/02)
Convenient syntheses of aryl diselenides 2, 1,2-benzisoselenazol-3(2H)-ones 4 and their 1-oxides 7 are reported.Reductive conversions of these compounds to bis(2-carbamoyl)phenyl diselenides 5 and oxidative cyclization of 5 to 1,2-benzisoselenazol-3(2H)-one 1-oxides 7 as the methods for the synthesis of these compounds are reported.Their ability to induce cytokines, such as TNF and IFN-γ, in human peripheral blood leucocyte cultures is described. - Key Words: 1,2-benzisoselenazol-3(2H)-ones/ Cytokine inducers/ Diselenides/ Interferon-gamma/ Tumor necrosis factor
Diselenobis-benzoic acid amides of primary and secondary amines and processes for the treatment of diseases in humans caused by a cell injury
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, (2008/06/13)
The present invention relates to new diselenobis-benzoic acid amides of primary and secondary amines of the general formula (I): STR1 and processes for the treatment of diseases in humans caused by a cell injury.
LITHIUM DISELENIDE IN APROTIC MEDIUM - A CONVENIENT REAGENT FOR SYNTHESIS OF ORGANIC DISELENIDES
Syper, Ludwik,Mlochowski, Jacek
, p. 6119 - 6130 (2007/10/02)
The reduction of selenium with lithium in THF in the presence of diphenylacetylene as a catalyst afforded lithium diselenide, which reacted with electrophiles giving alkyl or aryl diselenides 1 - 3 and selenides 4, as by-products.The useful method for preparation of diselenides based on this reaction was elaborated.
