124401-35-0

Basic information

• Product Name: methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>heptanoate
• Synonyms: methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>heptanoate
• CAS NO: 124401-35-0
• Molecular Weight: 419.537
• Mol File: 124401-35-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>heptanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>heptanoate(124401-35-0)
• EPA Substance Registry System: methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>heptanoate(124401-35-0)

Safety Data

• Hazardous Substances Data: 124401-35-0(Hazardous Substances Data)

Upstream product

• 124401-30-5 methyl 3(RS),5(SR)-dihydroxy-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>hept-6(E)-enoate 
• 5153-69-5 4-fluoro-β-nitrostyrene 
• 7152-15-0 ethyl 4-methyl-3-oxo-pentanoate 
• 459-57-4 4-fluorobenzaldehyde 
• 124401-56-5 methyl 5(RS)-hydroxy-3-oxo-7-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>hept-6(E)-enoate 
• 124401-44-1 1,2-diisopropyl-4-(4-fluorophenyl)-N-methyl-1H-pyrrole-3-carboxanilide 
• 124401-41-8 1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxanilide 
• 124401-50-9 ethyl 1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxylate 
• 124401-51-0 β-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>-(E)-acrylonitrile 
• 124401-53-2 3-<1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrol-3-yl>-(E)-propenal 
• 124401-46-3 1,2-diisopropyl-3-(hydroxymethyl)-4-(4-fluorophenyl)-1H-pyrrole 
• 124401-48-5 1,2-diisopropyl-4-(4-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 124401-39-4 3-(isopropylamino)-4-methylpent-2(E)-enoic acid anilide 
• 124401-38-3 4-methyl-3-oxo-N-phenylpentanamide 

Relevant articles and documents

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 2. Derivatives of 7-(1H-Pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) Acids

A series of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoates (-heptanoates) 1 and 2 have been prepared and tested for inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.The most potent compounds exceeded mevinolin's activity in vitro and in vivo.