1244030-03-2Relevant academic research and scientific papers
Domino rhodium(I)-catalysed reactions for the efficient synthesis of substituted benzofurans and indoles
Boyer, Alistair,Isono, Naohiro,Lackner, Sebastian,Lautens, Mark
supporting information; experimental part, p. 6468 - 6482 (2010/10/03)
Rhodium(I) catalysts promote the transformation of o-alkynyl phenols and anilines to the corresponding benzo[b]furans and indoles. The reaction is postulated to proceed via a transient 3-rhodium heterocycle intermediate, which can be trapped with suitable electrophiles to give poly-substituted heterocycles. In the case of mono-substituted electron-withdrawn electrophiles, excellent yield and selectivity for conjugate addition versus Heck-Mizoroki reaction can be achieved. In the case of 2-alkynyl pyridine electrophiles, novel 2-(benzofuran-3-yl)vinylpyridines are formed.
Synthesis of novel oxygen heterocycles: 1,10-dioxa-cyclopenta[a]fluorene and benzo[b]naphtho[2, 1-d]furans via D?tz intramolecular benzannulation
Sen, Subhabrata,Kulkarni, Parag,Borate, Kailaskumar,Pai, Nandini R.
scheme or table, p. 4128 - 4131 (2009/12/01)
Novel fused heterocycles 1,10-dioxa-cyclopenta[a]fluorene and benzo[b]naphtho[2, 1-d]furans were synthesized via D?tz intramolecular benzannulation of alkyne tethered aryloxy chromium Fischer carbenes.
