125345-27-9

Basic information

• Product Name: Phenol, 2-(1-hexynyl)-
• CAS NO: 125345-27-9
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Mol File: 125345-27-9.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(1-hexynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(1-hexynyl)-(125345-27-9)
• EPA Substance Registry System: Phenol, 2-(1-hexynyl)-(125345-27-9)

Safety Data

• Hazardous Substances Data: 125345-27-9(Hazardous Substances Data)

Upstream product

• 125345-26-8 1-hexynyl-2-(methoxymethoxy)benzene 
• 533-58-4 2-Iodophenol 
• 80778-47-8 1-iodo-2-methoxymethoxybenzene 
• 693-02-7 hex-1-yne 
• 1244030-03-2 2-(hex-1-yn-1-yl)phenyl acetate 
• 32865-61-5 2-iodophenyl acetate 

Downstream Products

• 1111078-59-1 (E)-1-(2-hydroxyphenyl)-2-(4-methylbenzylidene)hexan-1-one 
• 1111078-54-6 (E)-2-(4-chlorobenzylidene)-1-(2-hydroxyphenyl)hexan-1-one 
• 1111078-57-9 (E)-1-(2-hydroxyphenyl)-2-(4-nitrobenzylidene)hexan-1-one 
• 3226-15-1 1-(2-hydroxyphenyl)hexan-1-one 
• 1111078-43-3 (E)-2-benzylidene-1-(2-hydroxyphenyl)hexan-1-one 
• 448918-04-5 3-butyl-2-phenylchroman-4-one 
• 1111078-64-8 (E)-1-(2-hydroxyphenyl)-2-(naphthalen-2-ylmethylene)hexan-1-one 
• 1111078-52-4 (E)-2-(cyclohexylmethylene)-1-(2-hydroxyphenyl)hexan-1-one 
• 1442468-01-0 di-tert-butyl[2-(hex-1-yn-1-yl)phenoxy]silanol 
• 1609662-24-9 (12-butyl-6-phenyl-6H-naphtho[2,3-c]chromen-7-yl)diphenylphosphine oxide 

Relevant articles and documents

A Facile Construction of Bisheterocyclic Methane Scaffolds through Palladium-Catalyzed Domino Cyclization

A convenient palladium-catalyzed domino cyclization reaction for the construction of bis(benzofuranyl)methane scaffolds bearing an all-carbon quaternary center has been described. In the cascade process, one C(sp2)—O bond, two C(sp2)—C(sp3) bonds as well as two benzofuran rings are formed in a single synthetic sequence. The approach shows wide scope of substrates and good functional-group tolerance. Moreover, this methodology is successfully extended to the synthesis of benzofuranyl methyl chromane derivatives.

Ni-Catalyzed Cycloisomerization between 3-Phenoxy Acrylic Acid Derivatives and Alkynes via Intramolecular Cleavage and Formation of the C-O Bond to Give 2,3-Disubstituted Benzofurans

Reactions based on transition-metal-catalyzed C-O bond cleavage have attracted much attention as a new synthetic method. Until now, several intermolecular reactions via C-O bond cleavage of aryl ethers, alkenyl ethers, esters, and others have been reported. Here we report an unprecedented C-O bond cleavage of 3-phenoxy acrylic acid derivatives, followed by intramolecular C-O bond formation with alkynes. This reaction gave 2,3-disubstituted benzofurans having useful functional groups-silyl substituents and acrylic acid derivatives- A t the 2- A nd 3-positions, respectively. This report also described theoretical (DFT) insights into the mechanism.

Gold-Catalyzed Fluorination–Hydration: Synthesis of α-Fluorobenzofuranones from 2-Alkynylphenol Derivatives

The AuI-catalyzed fluorination–hydration of 2-alkynylphenol derivatives in the presence of Selectfluor [1-chloromethyl-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)] has been developed. This method provides straightforward a