1244040-10-5Relevant academic research and scientific papers
Formal nucleophilic substitution of bromocyclopropanes with amides en route to conformationally constrained β-amino acid derivatives
Prosser, Anthony R.,Banning, Joseph E.,Rubina, Marina,Rubin, Michael
, p. 3968 - 3971 (2010)
A chemo- and diastereoselective protocol for the formal nucleophilic substitution of 2-bromocyclopropylcarboxamides with secondary amides is described. This method allows for convergent and highly selective synthesis of trans-β-aminocyclopropane carboxylic acid derivatives.
