1244040-58-1Relevant academic research and scientific papers
Synthesis of lupinacidins A and B via sequential cycloaddition-double elimination
Sugimoto, Kohei,Enomoto, Masaru,Kuwahara, Shigefumi
, p. 4570 - 4572 (2010)
The first synthesis of lupinacidins A and B, tumor cell invasion inhibitors of microbial origin, has been achieved in four operational steps from 3-methoxy-2-methyl-2-cyclohexenone via the Diels-Alder cycloaddition of a conjugated cyclohexadiene derivative with a juglone-derived sulfinyl quinone followed by sequential elimination of a sulfenic acid and ethylene to afford protected forms of the target molecules.
