124455-24-9Relevant academic research and scientific papers
Reactivity Enhancement for Chiral Dirhodium(II) Tetrakis (Carboxamidates)
Doyle, Michael P.,Hu, Wenhao,Phillips, Iain M.,Moody, Christopher J.,Pepper, Adrian G.,Slawin, Alexandra M. Z.
, p. 112 - 117 (2001)
Difluorinated ligands from azetidinone-4-carboxylates and pyrrolidinone-5-carboxylate have been prepared, substituted onto dirhodium(II), and the reactivities and selectivities of the resulting catalysts have been examined. The fluorinated catalysts exhibit enhanced reactivity towards diazo decomposition but diminished enantioselectivities for cyclopropanation. Selectivity for ylide formation and rearrangement or Si-H insertion is enhanced or similar to that with unfluorinated analogues.
Total synthesis of (-)-4a,5-Dihydrostreptazolin
Cossy, Janine,Pevet, Isabelle,Meyer, Christophe
, p. 2841 - 2850 (2007/10/03)
(-)-4a,5-Dihydrostreptazolin has been synthesized in nine steps from D-glyceraldehyde acetonide. Key steps include a diastereoselective addition of a vinylic Grignard reagent to an imine derived from D-glyceraldehyde acetonide, a ring-closing metathesis, and a stereoselective radical-mediated enyne cyclization.
A short and efficient synthesis of (-)-4a,5-dihydrostreptazolin
Cossy, Janine,Pévet, Isabelle,Meyer, Christophe
, p. 122 - 124 (2007/10/03)
(-)-4a,5-Dihydrostreptazolin has been synthesized in 9 steps from D- glyceraldehyde acetonide. Key steps include a diastereoselective addition of a vinylic Grignard reagent onto an imine, a ring-closing metathesis and a highly stereoselective enyne radical-mediated cyclization.
