262284-59-3

Basic information

• Product Name: N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine
• Synonyms: N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine
• CAS NO: 262284-59-3
• Molecular Weight: 277.364
• Mol File: 262284-59-3.mol

Chemical Properties

• CAS DataBase Reference: N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine(262284-59-3)
• EPA Substance Registry System: N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine(262284-59-3)

Safety Data

• Hazardous Substances Data: 262284-59-3(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 2393-23-9 4-methoxy-benzylamine 
• 124455-21-6 [1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-meth-(E)-ylidene]-(4-methoxy-benzyl)-amine 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 262284-60-6 N-(but-3-enyl)-N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-enyl}-4-methoxybenzylamine 

Relevant articles and documents

Formal synthesis of dysiherbaine

A formal synthesis of dysiherbaine was achieved from D-mannitol using Grignard addition on chiral imine, RCM and Michael addition as key steps.

Total synthesis of (-)-4a,5-Dihydrostreptazolin

(-)-4a,5-Dihydrostreptazolin has been synthesized in nine steps from D-glyceraldehyde acetonide. Key steps include a diastereoselective addition of a vinylic Grignard reagent to an imine derived from D-glyceraldehyde acetonide, a ring-closing metathesis, and a stereoselective radical-mediated enyne cyclization.

A short and efficient synthesis of (-)-4a,5-dihydrostreptazolin

(-)-4a,5-Dihydrostreptazolin has been synthesized in 9 steps from D- glyceraldehyde acetonide. Key steps include a diastereoselective addition of a vinylic Grignard reagent onto an imine, a ring-closing metathesis and a highly stereoselective enyne radical-mediated cyclization.