124467-20-5

Basic information

• Product Name: 2-CHLORO-6-IODO-QUINOLINE
• Synonyms: 2-CHLORO-6-IODO-QUINOLINE;Quinoline, 2-chloro-6-iodo-
• CAS NO: 124467-20-5
• Molecular Formula: C₉H₅ClIN
• Molecular Weight: 289.5
• Product Categories: Quinoline series;CHIRAL CHEMICALS;Halides;Quinolines, Isoquinolines & Quinoxalines
• Mol File: 124467-20-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 349.321 °C at 760 mmHg
• Flash Point: 165.063 °C
• Appearance: /
• Density: 1.92g/cm³
• Vapor Pressure: 9.56E-05mmHg at 25°C
• Refractive Index: 1.726
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.43±0.43(Predicted)
• CAS DataBase Reference: 2-CHLORO-6-IODO-QUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-IODO-QUINOLINE(124467-20-5)
• EPA Substance Registry System: 2-CHLORO-6-IODO-QUINOLINE(124467-20-5)

Safety Data

• Hazardous Substances Data: 124467-20-5(Hazardous Substances Data)

Usage

General Description

2-CHLORO-6-IODO-QUINOLINE is a chemical compound with a molecular formula C9H6ClIN. It is a synthetic organic compound that belongs to the quinoline family and contains both chlorine and iodine atoms. This chemical is commonly used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. It has also been studied for its potential antimicrobial, anti-inflammatory, and antiparasitic properties. Due to its unique structure, 2-CHLORO-6-IODO-QUINOLINE has attracted attention in the field of medicinal chemistry and drug development. However, it is important to handle this compound with caution, as it may pose health and safety risks if not properly managed.

InChI:InChI=1/C9H5ClIN/c10-9-4-1-6-5-7(11)2-3-8(6)12-9/h1-5H

Upstream product

• 540-37-4 p-aminoiodobenzene 
• 296759-29-0 6-iodo-3,4-dihydroquinolin-2(1H)-one 
• 99455-01-3 6-iodo-2-hydroxyquinoline 
• 99455-01-3 6-iodoquinolin-2(1H)-one 
• 553-03-7 3,4-dihydro-2(1H)-quinolone 

Downstream Products

• 1567371-97-4 2-chloro-6-[3-(4-chlorophenyl)-2-[2-(trifluoromethoxy)phenyl]-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]quinoline 

Relevant articles and documents

Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1

6-Nitroquipazine has been known as one of the most potent and selective inhibitors of serotonin transporter in vitro and in vivo. Nine derivatives of 6-nitroquipazine were synthesized and tested for their potential abilities to displace [3H]citalopram binding to the rat cortical membranes. (C) 2000 Elsevier Science Ltd. All rights reserved.

Bicyclic aromatic substituted pyridone derivative

Disclosed is a compound represented by the formula (I): Wherein R1 and R2 independently represent a hydrogen atom, a lower alkyl group or the like; X1, X2 and X3 independently represent a methine group or a nitrogen atom; Y1 and Y3 independently represent a single bond, —O— or the like; Y2 represents a lower alkylene group or the like; W1 to W4 independently represent a single bond, a methylene group or the like; L represents a single bond, a methylene group or the like; Z1 and Z2 independently represent a single bond, a C1-4 alkylene group or the like; Ar1 represents an aromatic carbocyclic ring or the like; and Ar2 represents a bicyclic aromatic carbocyclic ring or the like. The compound is useful as a pharmaceutical for a central disease, a cardiovascular disease or a metabolic disease.

TRICYCLIC INHIBITORS OF 5-LIPOXYGENASE

Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of 5-lipoxygenase (5-LO). Also described herein are methods of using such 5-LO inhibitors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions, diseases, or disorders.