124513-25-3Relevant academic research and scientific papers
STUDY OF THE ANOMERIC EFFECT IN 2-SUBSTITUTED 1,3-DITHIANES
Juaristi, Eusebio,Tapia, Josefina,Mendez, Rodolfo
, p. 1253 - 1264 (1986)
The conformational analysis of several 2-substituted 1,3-dithianes made possible the evaluation of S-C-Y anomeric interactions, where Y=SCH3,SC6H5,CO2CH3,COC6H5,CO2H and N(CH3)2.The relative magnitude of the effects observed for these groups odithiane(Y)-ΔGocyclohexane(Y)> can be explained in terms of the combined influence of dipole/dipole and two-electron stabilizing interactions (stereoelectronic effect).
