1245240-41-8

Basic information

• Product Name: C₁₄H₁₁BrF₂N₂O₃S
• Synonyms: C₁₄H₁₁BrF₂N₂O₃S
• CAS NO: 1245240-41-8
• Molecular Weight: 405.22
• Mol File: 1245240-41-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₁BrF₂N₂O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₁BrF₂N₂O₃S(1245240-41-8)
• EPA Substance Registry System: C₁₄H₁₁BrF₂N₂O₃S(1245240-41-8)

Safety Data

• Hazardous Substances Data: 1245240-41-8(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

Synthesis and pharmacological evaluation of aryl aminosulfonamide derivatives as potent 5-HT6 receptor antagonists

A series of novel aryl aminosulfonamides was designed and synthesized as 5-HT6 receptor ligands. Many compounds screened in a functional reporter gene based assay displayed potent antagonistic activity with Kb values in the range of 0.02-10 nM. The lead compound 11m exemplified in this series showed good ADME surrogate properties, acceptable pharmacokinetic profile and is active in animal models of cognition like novel object recognition test and Morris water maze. The compound was selected for detailed profiling.