1245504-96-4

Basic information

• Product Name: 3-(4-methoxyphenyl)-1-(thiophen-3-yl)prop-2-en-1-one
• Synonyms: 3-(4-methoxyphenyl)-1-(thiophen-3-yl)prop-2-en-1-one
• CAS NO: 1245504-96-4
• Molecular Weight: 244.314
• Mol File: 1245504-96-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-1-(thiophen-3-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-1-(thiophen-3-yl)prop-2-en-1-one(1245504-96-4)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-1-(thiophen-3-yl)prop-2-en-1-one(1245504-96-4)

Safety Data

• Hazardous Substances Data: 1245504-96-4(Hazardous Substances Data)

Upstream product

• 1468-83-3 1-(thiophen-3-yl)-ethanone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1574828-51-5 2-(1-(4-methoxyphenyl)-3-oxo-3-(thiophen-3-yl)propyl)cyclopentanone 
• 1574828-60-6 4-(4-methoxyphenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine 
• 1373257-68-1 3-(4-methoxyphenyl)-3-(phenylthio)-1-(thiophen-3-yl)propan-1-one 
• 1205545-72-7 ethyl 6-(4-methoxyphenyl)-2-oxo-4-(thiophen-3-yl)cyclohex-3-enecarboxylate 

Relevant articles and documents

Unexpected lactonization accompanying addition of ethyl acetoacetate to chalcones derived from 3-acetylthiophene

Chalcone derivatives containing thiophene ring were prepared by the condensation of 3-acetylthiophene with aromatic aldehydes in excellent yields. The addition of ethyl acetoacetate to chalcone derivatives 3a-3h in the presence of solid NaOH in CH2Cl2 resulted in the formation of the mixture of bicyclic lactone derivatives 5a-5h and 6-(ethoxycarbonyl) cyclohexenone derivatives 6a-6h.

Potassium tert-butoxide catalyzed synthesis and characterization of novel 3-aryl-3-(phenylthio)-1-(thiophen-3-yl)propan-1-one derivatives

A series of thiophenyl-containing 3-thiophene derivatives (4a-4i) were prepared via the reaction of chalcone-analogua compounds (3a-3i) and thiophenol in the presence of catalytic amount of KOBu-t in CH2Cl2 with moderate to high yiel