1245507-48-5

Basic information

• Product Name: N,N'-p-methoxybenzylbiotin
• Synonyms: N,N'-p-methoxybenzylbiotin
• CAS NO: 1245507-48-5
• Molecular Weight: 484.616
• Mol File: 1245507-48-5.mol

Chemical Properties

• CAS DataBase Reference: N,N'-p-methoxybenzylbiotin(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-p-methoxybenzylbiotin(1245507-48-5)
• EPA Substance Registry System: N,N'-p-methoxybenzylbiotin(1245507-48-5)

Safety Data

• Hazardous Substances Data: 1245507-48-5(Hazardous Substances Data)

Upstream product

• 96666-59-0 cis-1,3-bis-(p-methoxy methoxybenzyl)tetrahydro-2H-furo[3,4-d]imidazole-2,4,6-trione 
• 1245507-44-1 methyl 5-[(3aS,4S,6aR)-1,3-bis(4-methoxybenzyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate 

Downstream Products

• 1245507-49-6 3-(N,N'-p-methoxybenzylbiotinoyl)oxazolidin-2-one 
• 58-85-5 biotin 

Relevant articles and documents

Preparation of (+)-biotin: Process development and scale-up

A practical asymmetric total synthesis of (+)-biotin based upon the chiral bifunctional sulfamide 8-promoted enantioselective anhydride desymmetrization has been achieved via the key chiral intermediacy of (3aS, 6aR)-1,3-bis(4-methoxybenzyl)tetrahydro-4H-thieno[3,4-d]imidazole-2,4(1H)-dione (4). In addition, the installation of the 4-carboxybutyl side chain at C-4 position of 4 was efficiently introduced by an improved C4+C1 strategy.

BIOMOLECULAR LABELLING USING MULTIFUNCTIONAL BIOTIN ANALOGUES

Novel biotin analogues, such as 2-Azidobiotin, comprising the ureido ring of natural biotin with the thiophene ring, optionally modified, and a modified sidechain having a functional end group, preferably selected from the group consisting of a carboxylic