124563-06-0Relevant articles and documents
Expeditious solution phase synthesis of fluoroquinolone antibacterial agents using polymer supported reagents
Hilty, Peter,Hubschwerlen, Christian,Thomas, Andrew W.
, p. 1645 - 1646 (2001)
The first example of a library synthesis of novel quinolone antibacterial agents using a polymer supported base (Amberlite 900-Cl) is described.
New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- or 3,4-disubstituted-1-pyrrolidinyl)quinoline-3-carboxylic acids
Hagen,Domagala,Heifetz,Sanchez,Solomon
, p. 849 - 854 (2007/10/02)
A series of 7-(3-amino- or 3-aminomethyl-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro- 4-oxo-3-quinolinecarboxylic acids was synthesized and tested for antibacterial activity. Unique to these quinolones was the presence of a methyl or phenyl gro
Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents
-
, (2008/06/13)
Disubstituted 7-pyrrolidinoquinoline- and -napthylridine-3-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.
Disubstituted-7-pyrrolidinonaphthyridine antibacterial agents
-
, (2008/06/13)
Disubstituted 7-pyrrolidinoquinoline- and -naphthyridine-3-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.