1245641-25-1

Upstream product

• 1245641-24-0 allyl 4-O-acetyl-2,3-di-O-benzoyl-α-L-fucopyranoside 
• 327593-87-3 allyl 4-O-acetyl-α-L-fucopyranoside 
• 41308-77-4 allyl α-L-fucopyranoside 

Downstream Products

• 1245641-29-5 allyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-2,3-di-O-benzoyl-α-L-fucopyranoside 

Relevant academic research and scientific papers

Nanoparticles to Study Lectins in Caenorhabditis elegans: Multivalent Galactose β1-4 Fucose-Functionalized Dendrimers Provide Protection from Oxidative Stress

Galectins are galactoside-binding lectins that are functional dimers or higher-order oligomers. Multivalent binding has been shown to augment the relatively low affinity of the galectins for their galactoside-binding partners, enabling the galectins to pl

Synthesis of fluorescence-labeled galβ1-3Fuc and Galβ1-4Fuc as Probes for the endogenous glyco-epitope recognized by galectins in caenorhabditis elegans

To search for the endogenous glyco-epitope in Caenorhabditis elegans, we synthesized labeled Galβ1-3Fuc and Galβ1-4Fuc and examined their binding affinity for C. elegans galectin LEC-6 using frontal affinity chromatography analysis. We developed a new strategy for synthesizing the labeled saccharides, in which the labeling unit, the 2-aminopyridine moiety, is coupled with a spacer unit derived from D-mannitol. Our results indicate that Galβ1-4Fuc is the endogenous glyco-epitope present in C. elegans N-glycans.