1245708-07-9

Upstream product

• 105640-07-1 4-(4-hydroxyphenyl)cyclohexan-1-one 
• 701232-66-8 [4-(4-hydroxyphenyl)cyclohexylidene]acetic acid methyl ester 
• 1245708-05-7 methyl 2-(4-(4-hydroxyphenyl)cyclohexyl)acetate 
• 67-56-1 methanol 

Downstream Products

• 701232-68-0 (trans)-methyl 2-(4-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)cyclohexyl)acetate 
• 1245708-06-8 methyl 2-((1s,4s)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclohexyl)acetate 

Relevant academic research and scientific papers

IMMUNOREGULATORY AGENTS

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Development of novel benzomorpholine class of diacylglycerol acyltransferase i inhibitors

Diacylglycerol acyltransferase 1 (DGAT1) presents itself as a potential therapeutic target for obesity and diabetes for its important role in triglyceride biosynthesis. Herein we report the rational design of a novel class of DGAT1 inhibitors featuring a