124576-24-5

Upstream product

• 651733-33-4 5-(2-bromophenyl)pent-4-ynoic acid benzhydryl ester 
• 583-53-9 2,3-dibromobenzene 
• 14221-01-3 tetrakis(triphenylphosphine) palladium⁽⁰⁾ 
• 6089-09-4 4-pentynoic acid 
• 583-55-1 1-Bromo-2-iodobenzene 
• 109-89-7 diethylamine 

Downstream Products

• 651733-34-5 (S)-2-[5-(2-Bromo-phenyl)-pent-4-ynoylamino]-propionic acid methyl ester 
• 651733-28-7 2-{5-[2-(3-tert-butoxycarbonylamino-prop-1-ynyl)-phenyl]-pent-4-ynoylamino}-propionic acid methyl ester 
• 124576-25-6 2-bromo-δ-oxobenzenepentanoic acid 

Relevant academic research and scientific papers

Synthesis and reactivity of enediynyl amino acids and peptides: a novel concept in lowering the activation energy of Bergman cyclisation by H-bonding and electrostatic interactions.

Novel enediynyl amino acids and peptides 3 and 5-8 were synthesized and their thermal reactivity towards Bergman cyclization studied and compared with the earlier reported amino acid 4, which demonstrated, for the first time, the effect of H-bonding and e

Furyl, phenylene, and thienyl leukotriene B4 analogues

This invention relates to a compound of the formula: STR1 or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, or --CH=CH--; wherein Z is OR1 or --NR4 R5 ; wherein R1 is hydrogen, lower alkyl, or a pharmaceutically acceptable cation; wherein R2 is H, --CH3 or --C2 H5 ; wherein R3 is OH, H or =O; wherein R4 and R5 may independently be hydrogen, or lower alkyl having 1-6 carbon atoms, or R4 and R5 may act together with N to form a cyclic amide of the formula: STR2 wherein n is an integer from 4-5; and m is an integer from 0-4. More particularly, this invention relates to compounds of the above formula which have utility as LTB4 antagonists.