1245819-87-7Relevant academic research and scientific papers
Rhodium-catalyzed asymmetric addition of arylboronic acids to β-nitroolefins: Formal synthesis of (S)-SKF 38393
Huang, Kung-Chih,Gopula, Balraj,Kuo, Ting-Shen,Chiang, Chien-Wei,Wu, Ping-Yu,Henschke, Julian P.,Wu, Hsyueh-Liang
supporting information, p. 5730 - 5733 (2013/12/04)
An efficient enantioselective addition of an array of arylboronic acids to various β-nitrostyrenes catalyzed by a novel and reactive rhodium-diene catalyst (S/C up to 1000) was developed, providing β,β- diarylnitroethanes in good to high yields (62-99%) with excellent enantioselectivities (85-97% ee). The method was extended to 2-heteroarylnitroolefins and 2-alkylnitroolefins similarly providing the desired products with high enantioselectivities and yields. The usefulness of this method was demonstrated in the formal synthesis of the enantiomer of the dopamine receptor agonist and antagonist, SKF 38393.
Rhodium-catalyzed asymmetric conjugate addition of arylboronic acids to nitroalkenes using olefin-sulfoxide ligands
Xue, Feng,Wang, Dongping,Li, Xincheng,Wan, Boshun
experimental part, p. 3071 - 3081 (2012/05/04)
An efficient rhodium/olefin-sulfoxide catalyzed asymmetric conjugate addition of organoboronic acids to a variety of nitroalkenes has been developed, where 2-methoxy-1-naphthyl sulfinyl functionalized olefin ligands have shown to be highly effective and a
Rhodium-catalyzed asymmetric conjugate addition of organoboronic acids to nitroalkenes using chiral bicyclo [3.3.0] diene ligands
Wang, Zhi-Qian,Feng, Chen-Guo,Zhang, Shu-Sheng,Xu, Ming-Hua,Lin, Guo-Qiang
supporting information; experimental part, p. 5780 - 5783 (2010/10/21)
(Figure Presented) Old before l diene: An efficient rhodium/ diene-catalyzed asymmetric conjugate addition of organoboronic acids to challenging nitroalkene substrates that lack α substituents has been developed. Chiral bicyclo[3.3.0] dienes were found to
