1245905-00-3Relevant academic research and scientific papers
3-benzyl-3-azabicyclo[3.1.1]heptan-6-one: A promising building block for medicinal chemistry
Denisenko, Aleksandr V.,Mityuk, Andrey P.,Grygorenko, Oleksandr O.,Volochnyuk, Dmytro M.,Shishkin, Oleg V.,Tolmachev, Andrey A.,Mykhailiuk, Pavel K.
supporting information; experimental part, p. 4372 - 4375 (2010/12/18)
Figure Presented. An efficient two-step multigram synthesis of the previously unknown 3-benzyl-3-azabicyclo[3.1.1]heptan-6-one is described. The compound is shown to be a promising building block for further selective derivatization of the cyclobutane ring providing novel conformationally restricted piperidine derivatives.
