1245905-80-9

Upstream product

• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 6048-29-9 triphenylphenacylphosphonium bromide 
• 1678-18-8 (2-oxo-2-phenylethyl)-triphenylphosphonium chloride 

Downstream Products

• 1245905-64-9 (R)-5-(4-bromophenyl)-5-(trifluoromethyl)-4,5-dihydro-3-phenylisoxazole 
• 1392505-69-9 (R)-3-(4-bromoephenyl)-4,4,4-trifluoro-1-phenylbutan-1-one 
• 1392505-37-1 (E)-3-(4-bromophenyl)-4,4,4-trifluoro-1-phenyl-2-buten-1-ol 
• 1380297-49-3 (R)-2-(4-bromophenyl)-4-oxo-4-phenyl-2-(trifluoromethyl)butanenitrile 

Relevant academic research and scientific papers

Catalytic Enantioselective Conjugate Alkynylation of β-Aryl-β-trifluoromethyl Enones Constructing Propargylic All-Carbon Quaternary Stereogenic Centers

The enantioselective conjugate alkynylation of β-aryl-β-trifluoromethyl enones has been carried out using terminal alkynes and diethylzinc in the presence of 3,3′-bis(perfluorophenyl)BINOL as the chiral ligand to give the corresponding ketones bearing a t

Synthesis of β-CF3 ketones from trifluoromethylated allylic alcohols by ruthenium catalyzed isomerization

This work describes the optimization process for the synthesis of β-trifluoromethylated ketones from trifluoromethylated allylic alcohols. This transformation proceeds through a ruthenium catalyzed isomerization under mild conditions with high atom econom

Ruthenium-catalyzed redox isomerization of trifluoromethylated allylic alcohols: Mechanistic evidence for an enantiospecific pathway

Transfer news: A synthetic approach to chiral β-CF3- substituted saturated carbonyl compounds has been developed in which ruthenium complexes efficiently catalyze the redox isomerization of CF3-bearing allylic alcohols by an intramol

Enantioselective synthesis of trifluoromethyl-substituted 2-isoxazolines: Asymmetric hydroxylamine/enone cascade reaction

(Figure Presented) Cuts both ways: The title reaction consists of an addition/cyclization/dehydration sequence and affords the biologically important chiral 3,5-diaryl-5-(trifluoromethyl)-2-isoxazolines 1 in excellent yields with high ee values. The flexi