1246016-16-9Relevant academic research and scientific papers
ARIPIPRAZOLE SALTS
-
Page/Page column 13, (2010/10/03)
Aripiprazole salts, consisting of aripiprazole and tricarboxylic acid derivative, wherein one carboxyl group of an acid forms ester with C1-C4-aliphatic alcohol, represented by formula (1), wherein is double bond and R is H, or is single bond and R is -O (C=O) R2, R2 is Ci-C4-aliphatic group or phenyl, optionally substituted by -CH3 or - OCH3 group in position 4 of the phenyl ring, n = 1 - 2, are new derivatives of antipsychotic effect. Aripiprazole salts are prepared in the reaction of aripiprazole free base and bicarboxylic acid anhydride in C1-C4 aliphatic alcohol as a solvent.
