124605-48-7

Upstream product

• 29892-37-3 chloro(dimethylsulfide) gold(I) 
• 30540-36-4 3,4-dimethyl-1-phenylphosphole 

Downstream Products

• 124605-50-1 iodo(1-phenyl-3,4-dimethylphosphole)gold(I) 
• 124605-49-8 bromo(1-phenyl-3,4-dimethylphosphole)gold(I) 
• 138917-06-3 (1-phenyl-3,4-dimethylphosphole)gold(III)Cl₃ 
• 124605-57-8 {(DMPP)4Au}⁽¹⁺⁾PF₆^(1-) 

Relevant academic research and scientific papers

Gold(I) complexes bearing phosphole ligands: Synthesis and antimalarial activity

A series of gold(I)-monophosphole complexes have been synthesized and characterized. The introduction of a nitrogen moiety in the complex structure was envisioned either by choosing the bis(trifluoromethanesulfonyl)imidate ligand as the X-ligand or by preparing a new pyrrolidinophosphole ligand as the L-ligand. All the complexes have been evaluated in?vitro for their antimalarial activity. These gold–phosphole complexes showed moderate activities with IC50 values ranging from 9.7 to 24?μM against Plasmodium falciparum chloroquine-resistant strains.

Gold phosphole complexes as efficient catalysts for alkyne activation

Gold(I) complexes bearing monophosphole ligands were synthesized, and their electronic and steric properties were compared to those of their triphenylphosphine-based counterparts. Cationic phosphole-based gold(I) complexes are active and selective in enyne cycloisomerization and in olefin cyclopropanation, with a good correlation between the ligand σ-donor ability and the catalytic activity. For the most efficient ligand, 1-phenyl-2,3,4,5-tetramethylphosphole (TMP), a highly active, selective, and stable cationic [Au(TMP)(CH3CN)]SbF6 complex was isolated.