1246189-51-4

Basic information

• Product Name: (E)-3-((3S)-6-benzyloxy-4-oxo-3-(acetoxymethyl)hexylidene)tetrahydropyran-2-one
• Synonyms: (E)-3-((3S)-6-benzyloxy-4-oxo-3-(acetoxymethyl)hexylidene)tetrahydropyran-2-one
• CAS NO: 1246189-51-4
• Molecular Weight: 374.434
• Mol File: 1246189-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-((3S)-6-benzyloxy-4-oxo-3-(acetoxymethyl)hexylidene)tetrahydropyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-((3S)-6-benzyloxy-4-oxo-3-(acetoxymethyl)hexylidene)tetrahydropyran-2-one(1246189-51-4)
• EPA Substance Registry System: (E)-3-((3S)-6-benzyloxy-4-oxo-3-(acetoxymethyl)hexylidene)tetrahydropyran-2-one(1246189-51-4)

Safety Data

• Hazardous Substances Data: 1246189-51-4(Hazardous Substances Data)

Upstream product

• 218282-19-0 3-(triphenylphosphoranylidene)tetrahydro-2H-pyran-2-one 
• 1246189-75-2 C₁₆H₂₀O₅ 

Downstream Products

• 1246189-94-5 (1S,2S,5S)-2-acetoxymethyl-1-(2-(benzyloxy)ethyl)-1-hydroxy-6-oxo-7-oxaspiro[4.5]decane 
• 1246189-57-0 (1R,2S,5R)-2-acetoxymethyl-1-(2-(benzyloxy)ethyl)-1-hydroxy-6-oxo-7-oxaspiro[4.5]decane 
• 1246189-50-3 (1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-2-hydroxy-3-(hydroxymethyl)-3-(3-hydroxypropyl)cyclopentane 

Relevant articles and documents

A stereoselective cyclisation cascade mediated by SmI2-H 2O: Synthetic studies towards stolonidiol

A cascade reaction involving sequential conjugate reduction, stereoselective aldol cyclisation and chemoselective lactone reduction mediated by SmI2-H2O provides access to a cyclopentanol bearing two vicinal quaternary stereocentres with good stereocontrol. The functionalised cyclopentanol product has been converted to a key intermediate in ongoing asymmetric studies towards stolonidiol.