218282-19-0Relevant academic research and scientific papers
Natural product biosynthesis inspired concise and stereoselective synthesis of benzopyrones and related scaffolds
Baskar, Baburaj,Dakas, Pierre-Yves,Kumar, Kamal
supporting information; experimental part, p. 1988 - 1991 (2011/06/25)
A natural product biosynthesis-inspired strategy to explore biologically relevant chemical space is presented. A phosphine-catalyzed cascade and stereoselective annulation provides a common tricyclic benzopyrone intermediate that was efficiently transformed into diverse and related naturally occurring scaffolds
A stereoselective cyclisation cascade mediated by SmI2-H 2O: Synthetic studies towards stolonidiol
Baker, Thomas M.,Sloan, Lisa A.,Choudhury, Lokman H.,Murai, Masahito,Procter, David J.
experimental part, p. 1246 - 1261 (2010/11/02)
A cascade reaction involving sequential conjugate reduction, stereoselective aldol cyclisation and chemoselective lactone reduction mediated by SmI2-H2O provides access to a cyclopentanol bearing two vicinal quaternary stereocentres with good stereocontrol. The functionalised cyclopentanol product has been converted to a key intermediate in ongoing asymmetric studies towards stolonidiol.
