1246307-86-7Relevant academic research and scientific papers
Synthesis of γ-functionalized allyltrichlorosilanes and their application in the asymmetric allylation of aldehydes
Malkov, Andrei V.,MacDonald, Claire,Koovsky, Pavel
, p. 1173 - 1175 (2010)
Isomerically pure trans-and cis-γ-bromoallyltrichlorosilanes 4 and 5 have been synthesized and shown to react with aromatic aldehydes 1 in the presence of Lewis-basic catalysts (e.g., DMF) to produce the corresponding anti-and syn-allylbromohydrins 8 and 9, respectively, as single diastereoisomers. With BINAPO 25 as a chiral catalyst, promising enantioselectivity (≤50% ee) has been attained.
