1246404-41-0Relevant academic research and scientific papers
Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents
Sravan Kumar,Alam,Gurrapu, Shirisha,Nelson, Grady,Williams, Michael,Corsello, Michael A.,Johnson, Joseph L.,Jonnalagadda, Subash C.,Mereddy, Venkatram R.
, p. 814 - 820 (2013/08/23)
Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.
Development of practical methodologies for the synthesis of functionalized benzoboroxoles
Kumar, J. Sravan,Bashian, Christopher M.,Corsello, Michael A.,Jonnalagadda, Subash C.,Mereddy, Venkatram R.
experimental part, p. 4482 - 4485 (2010/10/01)
2-Formylphenylboronic acids upon reaction with activated olefins such as acrylates, methyl vinyl ketone, and acrylonitrile provide functionalized benzoboroxoles. The corresponding homologated benzoboroxoles were synthesized via the reaction of 2-formylphenylboronic acids with α- bromomethylacrylates.
