1246405-84-4

Basic information

• Product Name: methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate
• Synonyms: methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate
• CAS NO: 1246405-84-4
• Molecular Weight: 361.644
• Mol File: 1246405-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate(1246405-84-4)
• EPA Substance Registry System: methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate(1246405-84-4)

Safety Data

• Hazardous Substances Data: 1246405-84-4(Hazardous Substances Data)

Upstream product

• 175137-42-5 Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 96232-71-2 4,5-dibromo-3-hydroxythiophene-2-carboxylic acid methyl ester 

Downstream Products

• 1246405-93-5 Methyl 5-(2-chlorophenyl)-4-(4-chlorophenyl)-3-[3-(tetrahydro-2H-pyran-2-yloxy)propoxy]thiophene-2-carboxylate 
• 1246405-94-6 5-(2-Chlorophenyl)-4-(4-chlorophenyl)-3-[3-(tetrahydro-2H-pyran-2-yloxy)propoxy]thiophene-2-carboxylic acid 
• 1246405-92-4 methyl 5-(2-chlorophenyl)-4-(4-chlorophenyl)-3-hydroxy-thiophene-2-carboxylate 

Relevant articles and documents

DERIVATIVES OF 3-ALKOXY-4,5-DIARYLTHIOPHENE-2-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

The invention relates to compounds of the formula (I), where: R1 is: a —NR5R6 group; an unsubstituted or substituted phenyl; R2 is: a (C1-C4)alkyl; an —X—R7 group; R3 and R4 each are independently a substituted phenyl; R5 is a hydrogen atom or a (C1-C4)alkyl; R6 is an unsubstituted or substituted (C1-C4)alkyl; or R5 and R6 together with the nitrogen atom to which they are bonded constitute an unsubstituted or substituted heterocyclic compound; X is a (C1-C5)alkylene; R7 is an —OR8 group, a —NR9R10 group, an —SO2—(C1-C4)alkyl group; R8 is a hydrogen atom or a (C1-C4)alkyl; R9 is a hydrogen atom or a (C1-C4)alkyl; R10 is a hydrogen atom, a —COR11 group, an —SO2R11 group or a —CO(CH2)mOH group; R11 is an unsubstituted or substituted (C1-C4)alkyl; m is 1, 2 or 3. The invention also relates to methods for preparing same and to the therapeutic use thereof.