124643-54-5Relevant academic research and scientific papers
Electrochemical-mediated cyclization of 2-alkynylanilines: A clean and safe synthesis of indole derivatives
Arcadi, Antonio,Bianchi, Gabriele,Inesi, Achille,Marinelli, Fabio,Rossi, Leucio
experimental part, p. 783 - 787 (2009/04/11)
The electrochemical-mediated annulation of 2-alkynylanilines to the corresponding indole derivatives proceeds in good yields and under conditions that avoid the use of metal catalysts or classical organic acids and bases. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Indol-2-yltributylstannane: A versatile reagent for 2-substituted indoles
Labadie,Teng
, p. 4250 - 4254 (2007/10/02)
A general method for 2-substituted indoles via the palladium-catalyzed coupling of indol-2-ylstannanes is described. (N-Methylindol-2-yl)tributylstannane (1) reacts with a variety of electrophiles under very mild conditions. [N-tert-Butoxycarbonyl)indol-2
Palladium-catalysed cyclization of 2-alkynylanilines to 2-substituted indoles under an acidic two-phase system
Cacchi, Sandro,Carnicelli, Veronica,Marinelli, Fabio
, p. 289 - 296 (2007/10/02)
The cyclization of 2-alkynylanilines in the presence of PdCl2 and n-Bu4NCl under an acidic CH2Cl2-HCl two-phase system affords 2-substituted indoles in good to high yield, at room temperature.The reaction is particularly suited to the one-flask preparatio
PALLADIUM-CATALYSED COUPLING OF ARYL AND VINYL TRIFLATES OR HALIDES WITH 2-ETHYNYLANILINE: AN EFFICIENT ROUTE TO FUNCTIONALIZED 2-SUBSTITUTED INDOLES
Arcadi, A.,Cacchi, S.,Marinelli, F.
, p. 2581 - 2584 (2007/10/02)
The palladium(O)-catalysed coupling of aryl and vinyl triflates or halides with the easily available 2-ethynylaniline, followed by a palladium(II)-catalysed cyclization step, provides an efficient and very versatile procedure for the synthesis of function
