122948-47-4Relevant articles and documents
Significant enhancement of the Stille reaction with a new combination of reagents-copper(I) iodide with cesium fluoride
Mee, Simon P. H.,Lee, Victor,Baldwin, Jack E.
, p. 3294 - 3308 (2005)
A systematic investigation for enhancement of Stille reaction using the combination of copper(I) iodide and cesium fluoride was described. Initial route to the target compound involved a double Stille coupling in the carbon-carbon bond formation of the key intermediate 1. Homocoupling has often been observed in this reaction especially when electron-withdrawing substituents are present in conjugation with tin. After extensive optimization, a variety of electronically unfavourable and sterically hindered substrates were coupled in very high yields under mild conditions.
Nickel-Catalyzed Arylation/Alkenylation of tert-Cyclobutanols with Aryl/Alkenyl Triflates via a C - C Bond Cleavage
Wang, Zhen,Hu, Yuanyuan,Jin, Hongwei,Liu, Yunkui,Zhou, Bingwei
, p. 466 - 474 (2020/12/22)
Herein, we first present a nickel-catalyzed arylation and alkenylation of tert-cyclobutanols with aryl/alkenyl triflates via a C-C bond cleavage. An array of γ-substituted ketones was obtained in moderate-to-good yields, thus featuring earth-abundant nick
Nickel-Catalyzed Decarboxylative Alkenylation of Anhydrides with Vinyl Triflates or Halides
Chen, Hui,Sun, Shuhao,Liao, Xuebin
supporting information, p. 3625 - 3630 (2019/05/24)
Decarboxylative cross-coupling of aliphatic acid anhydrides with vinyl triflates or halides was accomplished via nickel catalysis. This methodology works well with a broad array of substrates and features abundant functional group tolerance. Notably, our approach addresses the issue of safe and environmental installation of methyl or ethyl group into molecular scaffolds. The method possesses high chemoselectivity toward alkyl groups when aliphatic/aromatic mixed anhydrides are involved. Furthermore, diverse ketones could be modified with our strategy.