1246462-22-5Relevant academic research and scientific papers
An electrochemical multicomponent [3 + 1 + 1] annulations to synthesize polysubstituted 1,2,4-triazoles
Zhao, Zhiheng,He, Yonghui,Li, Ming,Xu, Jiazhe,Li, Xiangguang,Zhang, Lizhu,Gu, Lijun
, (2021)
An electrochemical multicomponent [3 + 1 + 1] annulation used for the synthesis of 1,3,5-trisubstituted 1,2,4-triazoles has been developed under transition-metal-, acid-, base- and external-oxidant-free conditions. In an undivided cell, a variety of hydrazones and aldehydes smoothly participate in this transformation to furnish a range of substituted 1,2,4-triazoles. The reaction constitutes a new transformation from hydrazones, aldehydes and NH4OAc into 1,2,4-triazoles, providing a unifying, simple and environmentally friendly approach to the currently available methods.
An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4-Triazole Scaffold Cyclic Compounds
Li, Wangyu,Liang, Xiao,Pan, Yuanjiang,Wang, Dungai,Xiong, Mingteng,Zhu, Heping
, (2022/02/02)
An electro-oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4-triazoles in satisfact
