1246465-86-0

Basic information

• Product Name: N-({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)acetamide
• Synonyms: N-({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)acetamide
• CAS NO: 1246465-86-0
• Molecular Weight: 283.25
• Mol File: 1246465-86-0.mol

Chemical Properties

• CAS DataBase Reference: N-({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)acetamide(1246465-86-0)
• EPA Substance Registry System: N-({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)acetamide(1246465-86-0)

Safety Data

• Hazardous Substances Data: 1246465-86-0(Hazardous Substances Data)

Upstream product

• 617-89-0 furan-2-ylmethanamine 
• 127-19-5 N,N-dimethyl acetamide 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 5663-62-7 N-(furan-2-ylmethyl)acetamide 

Relevant articles and documents

Palladium-catalysed direct 5-arylation of furfurylamine or 2-(aminoalkyl)-thiophene derivatives

The palladium-catalysed direct 5-arylation of furan or thiophene derivatives bearing CH2NHR substituents (with. R = COMe or CO 2tBu) generally proceeds in good yields by using a catalysts loading of only 0.1-2 mol-%. A wide range of functions such as acetyl, propionyl, formyl, ester, nitrile, trifluoromethyl or fluoro on the aryl bromide is tolerated. Higher yields were generally obtained in the presence of electron-deficient aryl bromides than with, electron-rich aryl bromides.