124650-87-9

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 124650-91-5 (1S,5R,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 6-chlorocarbonyl-naphthalen-2-yl ester 
• 124650-89-1 (1S,5R,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 6-methoxymethoxycarbonyl-naphthalen-2-yl ester 
• 124650-90-4 (1S,5R,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 6-carboxy-naphthalen-2-yl ester 
• 124650-93-7 methoxymethyl 6-acetoxy-2-naphthoate 
• 124650-97-1 methoxymethyl 6-hydroxy-2-naphthoate 
• 109216-50-4 (1S,5R,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carbonyl chloride 
• 17295-26-0 6-acetoxy-2-naphthoic acid 
• 16712-64-4 6-Hydroxy-2-naphthoic acid 

Downstream Products

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 124650-88-0 (1S,5R,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 6-{[(3aR,4R,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl]-carbamoyl}-naphthalen-2-yl ester 
• 124650-88-0 1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 6-{[(3aS,4S,6S,6aS)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl]-carbamoyl}-naphthalen-2-yl ester 

Relevant academic research and scientific papers

Kinetic studies and modeling of a self-replicating system

The design, synthesis, and study of a molecular template, 11a, that catalyzes its own formation from simpler components, 9 and 10d, is described. Autocatalysis is shown by the following: (1) the increase in rate of reaction of 9 and 10d in the presence of 11a; (2) the reduction in rate of reaction in the presence of 2,6-bis(acetylamino)pyridine inhibitor; and (3) the reduction in rate of reaction when a component incapable of template behavior, 10b, is substituted for 10d. Three kinetic pathways are elucidated: (1) the background bimolecular reaction (eq 6); (2) the preassociative mechanism (eq 7); and (3) the template termolecular process (eq 8). A kinetic model for the replication process is introduced, and equilibrium and rate constants are determined. Predictions for the shapes of the product growth curves are made.