1246624-41-8

Basic information

• Product Name: 4,5-dibromo-1-methyl-2-(4-methylphenyl)-1H-imidazole
• Synonyms: 4,5-dibromo-1-methyl-2-(4-methylphenyl)-1H-imidazole
• CAS NO: 1246624-41-8
• Molecular Weight: 330.022
• Mol File: 1246624-41-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,5-dibromo-1-methyl-2-(4-methylphenyl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dibromo-1-methyl-2-(4-methylphenyl)-1H-imidazole(1246624-41-8)
• EPA Substance Registry System: 4,5-dibromo-1-methyl-2-(4-methylphenyl)-1H-imidazole(1246624-41-8)

Safety Data

• Hazardous Substances Data: 1246624-41-8(Hazardous Substances Data)

Upstream product

• 1003-50-5 4,5-dibromo-1-methyl-1H-imidazole 
• 624-31-7 4-tolyl iodide 
• 1003-91-4 N-methyl-2,4,5-tribromoimidazole 
• 5720-05-8 4-methylphenylboronic acid 

Relevant articles and documents

Imidazole-Fused Enediynes by Selective C5-C4 Alkynylations of 4,5-Dibromoimidazoles

An efficient synthesis of symmetrical 1,2-disubstituted 4,5-dialkynylimidazoles by Sonogashira alkynylation of the corresponding 4,5-dibromo derivatives was developed. Moreover, through a careful tuning of the palladium ligand, unsymmetrical 1,2-disusbtituted 4,5-dialkynylimidazoles were also prepared through a regioselective C5 alkynylation of 4,5-dibromoimidazoles, followed by a second alkynylation involving the 4-bromo derivatives so obtained. This interesting class of imidazole-fused enediynes is also able to give thermal Bergman cycloaromatization (BC), as proved by DSC experiments.

Synthesis of 2,5,6-trisubstituted benzimidazoles by heck and subsequent 6π-electrocyclization-dehydrogenation reactions of 2,4,5-tribromo-n- methylimidazole and 2-Aryl-4,5-dibromo-N-methylimidazoles

2,5,6-Trisubstituted benzimidazoles were prepared by Heck reactions of 2,4,5-tribromo-N-methylimidazole and 2-aryl-4,5-dibromo-N-methyl-imidazoles and subsequent 6π-electrocyclization-dehydrogenation reactions. Georg Thieme Verlag Stuttgart.