124665-84-5

Upstream product

• 124665-88-9 (R)-2-Oxo-3-phenylselanyl-5-trityloxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 124665-81-2 (R)-1-(tert-butoxycarbonyl)-5-trityloxymethyl-2-pyrrolidinone 
• 124665-82-3 (R)-1-(tert-butoxycarbonyl)-2-oxo-5-trityloxymethyl-3-pyrroline 
• 124665-91-4 (R)-5-trityloxymethyl-2-pyrrolidinone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 124665-83-4 (3S,4S,5S)-1-(tert-butoxycarbonyl)-3,4-dihydroxy-5-trityloxymethyl-2-pyrrolidinone 
• 77-76-9 2,2-dimethoxy-propane 
• 124665-82-3 (S)-2-Oxo-5-trityloxymethyl-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 127298-73-1 (3R,4R,5R)-3,4-Dihydroxy-2-oxo-5-trityloxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 212892-08-5 (4R,5R)-5-((R)-1-tert-Butoxycarbonylamino-2-trityloxy-ethyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester 
• 124665-87-8 (3S,4S₅S)-3-(benzyloxycarbonyl)amino-5-ethoxycarbonyl-5-hydroxy-4-pentanolide 
• 124665-90-3 (2S,3S,4R)-1-(tert-butoxycarbonyl)-3,4-isopropylidenedioxy-5-trityloxymethylpyrrolidine 
• 154905-23-4 (2R,3R,4S)-N-(tert-butoxycarbonyl)-3,4-isopropylidenedioxy-2-trityloxymethylpyrrolidine 
• 212892-38-1 (3aS,4S,6R,6aR)-4-((R)-1-Methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-32-5 (3aS,4S,6R,6aR)-4-((S)-1-Methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-11-0 (3aS,4S,6R,6aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-30-3 (2R,3R,4S,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-36-9 (2R,3R,4S,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1R)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-13-2 (2R,3R,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-vinylpyrrolidine 
• 262370-57-0 {(R)-1-[(4R,5S)-5-((R)-1-Hydroxy-allyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-trityloxy-ethyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereocontrolled synthesis of 1,7a-diepialexine

(2R,5R)-Dihydroxymethyl-(3R,4S)-dihydroxypyrrolidine derivative 15, 1,7a-diepialexine 1, and 1,7,7a-triepialexine 2 have been synthesized from (S)-pyroglutamic acid derivative 4.

Synthesis of (2S,3S,4S)-4-Amino-2,3-dihydroxyhexanedioic Acid Derivatives from (R)-Pyroglutamic Acid

(2S,3S,4S)-4-Amino-2,3-dihydroxyhexanedioic acid derivatives (11 and 12) were synthesized from an (R)-pyroglutamic acid derivative (3) by cis-dihydroxylation of the α,β-unsaturated lactam (4) as the key reaction.Keywords AI-77-B; chiral synthesis; (2S,3S,