212892-13-2

Upstream product

• 126199-70-0 [(R)-1-((4R,5R)-5-Acryloyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-trityloxy-ethyl]-carbamic acid tert-butyl ester 
• 124665-84-5 (3R,4R,5R)-1-(tert-butoxycarbonyl)-3,4-isopropylidenedioxy-5-trityloxymethyl-2-pyrrolidinone 
• 205653-01-6 {(R)-1-[(4R,5S)-5-(1-Hydroxy-allyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-trityloxy-ethyl}-carbamic acid tert-butyl ester 

Downstream Products

• 212892-38-1 (3aS,4S,6R,6aR)-4-((R)-1-Methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-32-5 (3aS,4S,6R,6aR)-4-((S)-1-Methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-30-3 (2R,3R,4S,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-36-9 (2R,3R,4S,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1R)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-28-9 (2R,3R,4S,5R)-N-benzyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-methoxymethyloxy-3-hydroxypropanyl)pyrrolidine 
• 212892-24-5 (3aS,4R,6R,6aR)-4-((R)-1-Methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester 
• 212892-17-6 (2R,3R,4S,5R)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-methoxymethyloxy-3-butenyl)pyrrolidine 
• 142406-04-0 (3aS,4R,6R,6aR)-5-Benzyl-4-((R)-1-methoxymethoxy-but-3-enyl)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole 
• 142406-04-0 (2R,3R,4S,5R)-N-benzyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-methoxymethyloxy-3-butenyl)pyrrolidine 
• 212892-15-4 (2R,3R,4S,5R)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1S)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-21-2 (2R,3R,4S,5R)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-((1R)-1-hydroxy-3-butenyl)pyrrolidine 
• 212892-50-7 (2R,3R,4S,5S)-N-tert-butoxycarbonyl-3,4-isopropylidenedioxy-2-trityloxymethyl-5-hydroxymethylpyrrolidine 

Relevant academic research and scientific papers

Stereoselective synthesis of alexine stereoisomers from (S)- pyroglutamic acid

Four stereoisomers of alexine (1,7a-diepialexine (1a), 1,7,7a- triepialexine (1b), 1-epialexine (30a), and 1,7-diepialexine (30b)), the polyhydroxylaled pyrrolizidine alkaloid, were synthesized from (S)- pyroglutamic acid derivative (6).