1246738-45-3Relevant academic research and scientific papers
Study on the structure-activity relations of pleuromutilin derivatives with an aromatic amide and a thioether group in the C14 side chain
Xu, Ke-Ping,Zhang, Yuan-Yuan,Luo, Juan,Chen, Shan-Li,Wang, Yu-Liang
experimental part, p. 354 - 357 (2010/10/21)
Nine novel pleuromutilin derivatives having benzamide substituents have been synthesised permitting structureactivity relations of pleuromutilin derivatives with aromatic amide and thioether groups in the C14 side chain to be studied. The results showed that the heterocyclic carboxamide group was necessary to enhance bio-activities.
