1246763-86-9

Upstream product

• 1246763-83-6 1,4,6-tri-O-acetyl-2,3-dideoxy-L-erythro-hexopyranose 
• 108-98-5 thiophenol 

Downstream Products

• 60873-27-0 C₁₀H₁₄O₅ 
• 1246763-89-2 (N6-benzoyladenin-9-yl) 4,6-di-O-acetyl-1,2,3-trideoxy-β-L-erythro-hexopyranoside 
• 1246763-92-7 (N6-benzoyladenin-9-yl) 4,6-di-O-acetyl-1,2,3-trideoxy-α-L-erythro-hexopyranoside 
• 1447068-04-3 1-(5-hydroxy-6-[(4-methoxyphenyl)(diphenyl)methoxy]methyltetrahydro-2H-2-pyranyl)-1,2,3,4-tetrahydro-2,4-pyrimidinedione 

Relevant academic research and scientific papers

Enantiomeric selection properties of β-homoDNA: Enhanced pairing for heterochiral complexes

De gustibus: β-homoDNA has the singular property of being able to pair with homochiral complements of opposite chirality, with a greater stability than that observed in the corresponding isochiral complexes. Relevant to etiological investigations on nucleic acid structure, these results suggest the existence of a relationship between carbohydrate structure and stereoselectivity of the hybridization processes of the corresponding nucleic acids. Copyright

Toward l-homo-DNA: Stereoselective de novo synthesis of β-L-erythro-hexopyranosyl nucleosides

A novel route to 2′,3′-dideoxy-β-l-erythro-hexopyranosyl nucleosides equipped with a 1′-(N6-benzoyladenin-9-yl) or a 1′-(thymin-1-yl) moiety has been developed. Synthesis of the enantiopure sugar moiety was carried out by a de novo approach based on a domino reaction as the key step. N-Glycosidation was explored via either nucleobase-transfer mechanism (B = T) or in situ anomerization (B = A or T), affording target nucleosides with high overall stereoselectivity.