60873-27-0

Upstream product

• 4005-49-6 N-benzoyladenine 
• 1246763-86-9 4,6-di-O-acetyl-1,2,3-trideoxy-1-(phenylsulfinyl)-L-erythro-hexopyranose 
• 1246763-79-0 methyl 4,6-di-O-acetyl-2,3-dideoxy-α-L-erythro-hexopyranoside 

Downstream Products

• 1332628-34-8 (4S,6R,4aS,8aR)-acetic acid 6-acetoxy-2-phenyl-4-p-tolyl-4a,6,7,8a-tetrahydro-4H,5H-pyrano[3,2-e][1,3]oxazin-7-ylmethyl ester 
• 1332628-33-7 (4S,6R,4aS,8aR)-acetic acid 6-acetoxy-4-naphthalen-1-yl-2-phenyl-4a,6,7,8a-tetrahydro-4H,5H-pyrano[3,2-e][1,3]oxazin-7-ylmethyl ester 
• 1332628-32-6 (4S,6R,4aS,8aR)-acetic acid 7-acetoxymethyl-2,4-diphenyl-4a,6,7,8a-tetrahydro-4H,5H-pyrano[3,2-e][1,3]oxazin-6-yl ester 

Relevant academic research and scientific papers

Toward l-homo-DNA: Stereoselective de novo synthesis of β-L-erythro-hexopyranosyl nucleosides

A novel route to 2′,3′-dideoxy-β-l-erythro-hexopyranosyl nucleosides equipped with a 1′-(N6-benzoyladenin-9-yl) or a 1′-(thymin-1-yl) moiety has been developed. Synthesis of the enantiopure sugar moiety was carried out by a de novo approach based on a domino reaction as the key step. N-Glycosidation was explored via either nucleobase-transfer mechanism (B = T) or in situ anomerization (B = A or T), affording target nucleosides with high overall stereoselectivity.