1246775-87-0Relevant academic research and scientific papers
One-Pot, Three-Step Synthesis of Benzoxazinones via Use of the Bpin Group as a Masked Nucleophile
Larin, Egor M.,Torelli, Alexa,Loup, Joachim,Lautens, Mark
, p. 2720 - 2725 (2021/04/05)
The utilization of the Bpin group as a pronucleophile to facilitate the assembly of cyclic carbamates has been achieved. This one-pot process involves an initial copper-catalyzed borylation, a subsequent C-B bond oxidation to generate the reactive alcohol
Synthesis of substituted indole from 2-aminobenzaldehyde through [1,2]-aryl shift
Levesque, Patrick,Fournier, Pierre-Andre
supporting information; experimental part, p. 7033 - 7036 (2010/11/18)
A mild, efficient, and simple method for the synthesis of 3-ethoxycarbonylindoles has been developed. Addition of ethyl diazoacetate (EDA) to 2-aminobenzaldehydes cleanly affords the indole core. As opposed to other common approaches for the synthesis of indole, this method displays both excellent functional group tolerance and perfect regiochemical control. This allowed the synthesis of a variety of useful indole building blocks from 2-aminobenzaldehydes derived from readily available anthranilic acids.
