1246811-33-5Relevant academic research and scientific papers
Iodine-Mediated Direct Generation of o-Quinone Methides at Room Temperature: A Facile Protocol for the Synthesis of ortho-Hydroxybenzyl Thioethers
Basha, R. Sidick,Chen, Chia-Wei,Reddy, Daggula Mallikarjuna,Lee, Chin-Fa
, p. 2475 - 2483 (2018)
An iodine-mediated preparation of ortho-quinone methides (o-QMs) from ortho-hydroxybenzyl alcohols by a C?O bond scission strategy is described. The in situ generated o-QMs were then employed for C?S bond formation by thio-Michael addition of thiols to provide the ortho-hydroxybenzyl thioethers (o-HBT) in moderate to excellent yields.
