1246854-95-4

Basic information

• Product Name: (E)-1,3-diphenyl-3-({[(E)-1-(2-thienyl)ethylidene]amino}oxy)-2-propen-1-one
• CAS NO: 1246854-95-4
• Molecular Weight: 347.437
• Mol File: 1246854-95-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1,3-diphenyl-3-({[(E)-1-(2-thienyl)ethylidene]amino}oxy)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,3-diphenyl-3-({[(E)-1-(2-thienyl)ethylidene]amino}oxy)-2-propen-1-one(1246854-95-4)
• EPA Substance Registry System: (E)-1,3-diphenyl-3-({[(E)-1-(2-thienyl)ethylidene]amino}oxy)-2-propen-1-one(1246854-95-4)

Safety Data

• Hazardous Substances Data: 1246854-95-4(Hazardous Substances Data)

Upstream product

• 1956-45-2 2-acetylthiophene oxime 
• 7338-94-5 1,3-diphenyl-2-propynone 

Relevant articles and documents

Triphenylphosphine as an effective catalyst for ketoximes addition to acylacetylenes: Regio- and stereospecific synthesis of (E)-(O)-2-(acyl) vinylketoximes

Triphenylphosphine catalyzes the regio- and stereospecific addition of ketoximes to acylacetylenes, whereas classical conditions using acetylene (KOH/DMSO, 70 °C) are unsuitable for this purpose. The reaction proceeds under mild conditions (CH2Cl2, rt, 7 h) to afford (E)-(O)-2-(acyl)vinylketoximes (92-98% stereoselectivity) in a yield of up to 85%. The (E)-adducts obtained are energetically less favorable than the corresponding (Z)-isomers and are gradually enriched with (Z)-isomers, thus indicating the kinetic control of (E)-stereoselectivity of the reaction.