1246922-88-2 Usage
Uses
Used in Pharmaceutical Industry:
2-((5-bromopyrimidin-2-yl)oxy)ethan-1-ol is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its specific application is in the synthesis of macitentan, an endothelin receptor antagonist, which is utilized in the treatment of pulmonary arterial hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 1246922-88-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,9,2 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1246922-88:
(9*1)+(8*2)+(7*4)+(6*6)+(5*9)+(4*2)+(3*2)+(2*8)+(1*8)=172
172 % 10 = 2
So 1246922-88-2 is a valid CAS Registry Number.
1246922-88-2Relevant academic research and scientific papers
One-pot etherification of purine nucleosides and pyrimidines
Kokatla, Hari Prasad,Lakshman, Mahesh K.
supporting information; experimental part, p. 4478 - 4481 (2010/12/24)
A one-pot synthesis of ethers derived from inosine, guanosine, 2′-deoxyguanosine, and pyrimidinones is described. Exposure of the heterocycle to 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and Cs2CO3/s
