1247018-67-2

Basic information

• Product Name: [N-{2-(2,6-difluoro-4-cyanophenyl)-aminoethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide
• Synonyms: [N-{2-(2,6-difluoro-4-cyanophenyl)-aminoethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide
• CAS NO: 1247018-67-2
• Molecular Weight: 516.575
• Mol File: 1247018-67-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [N-{2-(2,6-difluoro-4-cyanophenyl)-aminoethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: [N-{2-(2,6-difluoro-4-cyanophenyl)-aminoethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide(1247018-67-2)
• EPA Substance Registry System: [N-{2-(2,6-difluoro-4-cyanophenyl)-aminoethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide(1247018-67-2)

Safety Data

• Hazardous Substances Data: 1247018-67-2(Hazardous Substances Data)

Upstream product

• 1247018-10-5 [N-(2-aminoethyl)-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide 
• 134227-45-5 3,4,5-trifluorobenzonitrile 

Downstream Products

• 1247018-49-0 [N-{2-[(2,6-difluoro-4-cyanophenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-ethyl}-N-{N-(2-pyrimidinyl)-piperidin-4-ylmethyl}]-1-methyl-1H-imidazole-4-sulfonamide 

Relevant articles and documents

Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents

A potent class of anticancer, human farnesyltransferase (hFTase) inhibitors has been identified by "piggy-backing" on potent, antimalarial inhibitors of Plasmodium falciparum farnesyltransferase (PfFTase). On the basis of a 4-fold substituted ethylenediam