124770-80-5

Upstream product

• 127696-10-0 trans-3,3-diethoxy-1,2-cyclobutanedicarboxylic acid diethyl ester 
• 15210-38-5 (trans)-3,3-diethoxy-1,2-cyclobutanedicarboxylic acid,diethyl ester 
• 124770-79-2 C₂₄H₂₈O₆ 
• 124770-79-2 C₂₄H₂₈O₆ 
• 126261-70-9 (+/-)-trans-1,2-bis-(3,3-diethoxycyclobutylen)methanol 

Downstream Products

• 124770-85-0 (+/-)-9-<(1β,2α,3β)-2,3-bis(hydroxymethyl)-1-cyclobutyl>adenine 
• 124770-83-8 1-(cyclohexylcarbonyl)amino-3-(cyclohexylcarbonyloxy)methyl-2-cyclobutanemethanol 
• 124770-85-0 cis-trans-9-<2,3-bis-(hydroxymethyl)cyclobutyl>adenine 
• 124770-82-7 (1,2-cis)-1-amino-2,3-bis(cyclohexylcarbonyloxymethyl)cyclobutane 
• 124770-82-7 (1,2-trans)-1-amino-2,3-bis(cyclohexylcarbonyloxymethyl)cyclobutane 
• 124770-84-9 C₂₅H₃₅N₅O₄ 
• 124770-84-9 C₂₅H₃₅N₅O₄ 
• 124794-61-2 C₂₅H₃₃ClN₄O₄ 
• 124794-61-2 C₂₅H₃₃ClN₄O₄ 
• 126261-73-2 C₂₀H₂₀O₅ 
• 124770-81-6 trans-2,3-bis-(benzoyloxymethyl)cyclobutanone oxime 
• 126261-73-2 C₂₀H₂₀O₅ 

Relevant academic research and scientific papers

CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS

Described herein are cyclobutyl nucleoside analogs of Formula (I), pharmaceutical compositions that include one or more cyclobutyl nucleoside analogs and methods of using the same to treat HBV, HDV and/or HIV.

Synthesis of SQ-33,054, a novel cyclobutane nucleoside with potent antiviral activity

The racemic, guanine-containing cyclobutane nucleoside SQ-33,054 (3) was synthesized in 8 steps from the cyclobutane diester 4.