126261-70-9

Usage

Physical state

Colorless liquid

Odor

Faint, sweet

Primary use

Chemical intermediate or solvent

Applications

a. Production of polymers and resins
b. Synthesis of pharmaceuticals

Stability

Relatively stable under normal conditions

Reactivity

May react violently with strong oxidizing agents

Health hazards

a. Skin irritation
b. Eye irritation
c. Respiratory system irritation

Safety precautions

Handle with appropriate safety measures

Upstream product

• 2678-54-8 ketene diethyl acetal 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 127696-10-0 trans-3,3-diethoxy-1,2-cyclobutanedicarboxylic acid diethyl ester 

Downstream Products

• 126261-73-2 C₂₀H₂₀O₅ 
• 124770-80-5 trans-2,3-bis(benzoyloxymethyl)cyclobutanone 
• 142343-73-5 (+/-)-(1α,2α,3β)-2,3-bis<(benzyloxy)methyl>cyclobutanol 
• 142434-69-3 (+)-(1S,2S,3S)-2,3-bis<(benzyloxy)methyl>-1-cyclobutanol 
• 142343-73-5 (-)-(1R,2R,3R)-2,3-bis<(benzyloxy)methyl>-1-cyclobutanol 
• 142343-78-0 (+)-(1R,2S,3S)-2-amino-7-<2,3-bis<(benzyloxy)methyl>cyclobutyl>pyrrolo<2,3-d>-pyrimidin-4(3H)-one 
• 142343-77-9 (+)-(1R,2S,3S)-2-amino-7-<2,3-bis<(benzyloxy)methyl>cyclobutyl>-4-chloropyrrolo<2,3-d>-pyrimidine 
• 142343-74-6 (+)-(1S,2S,3S)-2,3-bis<(benzyloxy)methyl>-1-cyclobutyl tosylate 
• 142343-75-7 C₂₀H₂₃N₃O₂ 
• 142343-72-4 (+)-(1S,2S,3S)-2,3-bis<(benzyloxy)methyl>-1-cyclobutyl acetate 
• 132164-72-8 trans-2,3-bis<(benzyloxy)methyl>cyclobutanone 
• 142343-76-8 (+)-(1R,2S,3S)-2,3-bis<(benzyloxy)methyl>cyclobutylamine 

Relevant academic research and scientific papers

CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS

Described herein are cyclobutyl nucleoside analogs of Formula (I), pharmaceutical compositions that include one or more cyclobutyl nucleoside analogs and methods of using the same to treat HBV, HDV and/or HIV.

Synthetic studies toward providencin: Efficient construction of a furanyl-cyclobutanone fragment

Described is the construction of a furanyl-cylcobutanone fragment suited for incorporation into a synthesis of the naturally occurring anti-cancer agent Providencin.

Synthesis of SQ-33,054, a novel cyclobutane nucleoside with potent antiviral activity

The racemic, guanine-containing cyclobutane nucleoside SQ-33,054 (3) was synthesized in 8 steps from the cyclobutane diester 4.