124786-85-2Relevant academic research and scientific papers
Boron-catalyzed CC functionalization of allyl alcohols
Rao, Santhosh,Kapanaiah, Raja,Prabhu, Kandikere Ramaiah
, p. 1301 - 1306 (2019)
Tris(pentafluorophenyl)borane-catalyzed CC bond functionalization of arylallyl alcohols using donor-acceptor carbenes is presented. The allylic hydroxyl group is found to assist the product formation by neighboring group participation providing a clue towards mechanistic understanding. This method can also be employed to effect homologation of allyl alcohols to homoallyl alcohols. Overall, this metal-free transformation presents a novel disconnection strategy towards carbon-carbon bond scission and formation.
On the Acylation of Hydroxy- and Mercaptocarboxylic Acid Esters Using the Carbodiimide/Acylation Catalyst Method
Rao, Nagaraj N.,Roth, Hermann J.
, p. 523 - 530 (2007/10/02)
Acylation of esters of hydroxycarboxylic acids can be carried out easily and in good yields by using the carbodiimide/acylation catalyst method.The reaction has also been applied to dihydroxy- and mercaptocarboxylic acid esters.The compounds formed from certain esters of hydroxycarboxylic acids are unstable to heat and decompose easily to free carboxylic acids.Use of racemic carboxylic acids leads to diastereomers, whose (1)H-NMR shifts for characteristic protons are different as expected.Five drugs are among the carboxylic acids investigated in this context.
