1247884-87-2

Upstream product

• 501-53-1 benzyl chloroformate 
• 694-05-3 1,2,3,6-tetrahydropyridine 
• 66207-23-6 1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine 
• 167096-99-3 3,4-dihydroxypiperidine-1-carboxylic acid benzyl ester 
• 1247884-85-0 benzyl 4-azido-3-methanesulfonyloxypiperidine-1-carboxylate 

Downstream Products

• 1247884-89-4 benzyl 3,4-diaminopiperidine-1-carboxylate 

Relevant academic research and scientific papers

BETA-LACTAMASE INHIBITORS

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuromuscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.