167096-99-3

Basic information

• Product Name: (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE
• Synonyms: (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE;Benzyl (3S,4R)-3,4-dihydroxypiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 3,4-dihydroxy-, phenylMethyl ester, (3R,4S)-rel-;RNUMISHXYWFZCE-NEPJUHHUSA-N
• CAS NO: 167096-99-3
• Molecular Formula: C13H17NO4
• Molecular Weight: 251.28
• Mol File: 167096-99-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 410.363°C at 760 mmHg
• Flash Point: 201.98°C
• Appearance: /
• Density: 1.324g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.604
• PKA: 14.21±0.40(Predicted)
• CAS DataBase Reference: (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE(167096-99-3)
• EPA Substance Registry System: (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE(167096-99-3)

Safety Data

• Hazardous Substances Data: 167096-99-3(Hazardous Substances Data)

Usage

General Description

(3S,4R)-Benzyl 3,4-dihydropyridine-1-carboxylate is a chemical compound with a molecular structure containing a piperidine ring with hydroxyl and carboxyl groups, as well as a benzyl moiety. It is a stereoisomer with a specific orientation of its substituent groups, denoted by the (3S,4R) designation. (3S,4R)-BENZYL 3,4-DIHYDROXYPIPERIDINE-1-CARBOXYLATE has potential applications in organic synthesis and medicinal chemistry, where it can be used as a building block or intermediate for the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure and stereochemistry make it a valuable molecule for research and development in the field of organic chemistry and drug discovery.

InChI:InChI=1/C13H17NO4/c15-11-6-7-14(8-12(11)16)13(17)18-9-10-4-2-1-3-5-10/h1-5,11-12,15-16H,6-9H2/t11-,12+/m1/s1

Upstream product

• 66207-23-6 1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine 
• 694-05-3 1,2,3,6-tetrahydropyridine 
• 1624258-63-4 rac-benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 501-53-1 benzyl chloroformate 
• 66207-08-7 3,4-epoxy-piperidine-1-carboxylic acid benzyl ester 
• 108-05-4 vinyl acetate 
• 167096-99-3 (+/-)-trans-1-benzyloxycarbonyl-3,4-dihydroxypiperidine 
• 37088-07-6 1,4,5-trideoxy-1,5-imino-D-threo-pentitol 
• 266688-38-4 methyl 2,3-di-O-acetyl-4-cyano-4-deoxy-D-threonate 
• 266688-39-5 5-amino-2,3-di-O-acetyl-4,5-dideoxy-D-threo-pentono-1,5-lactam 
• 266688-37-3 methyl 4-cyano-4-deoxy-D-threonate 
• 266688-40-8 5-amino-4,5-dideoxy-D-threo-pentono-1,5-lactam 
• 886847-37-6 (3R,4R)-3-acetoxy-1-benzyloxycarbonyl-4-hydroxypiperidine 
• 443648-89-3 (-)-(3R,4R)-3,4-dihydroxypiperidine hydrochloride 

Downstream Products

• 1247884-87-2 3,4-diazidopiperidine-1-carboxylic acid benzyl ester 
• 1247884-89-4 benzyl 3,4-diaminopiperidine-1-carboxylate 
• 37088-07-6 (3S,4R)-piperidine-3,4-diol 
• 37088-07-6 1,4,5-trideoxy-1,5-imino-D-threo-pentitol 

Relevant articles and documents

BETA-LACTAMASE INHIBITORS

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Glycosynthase-Mediated Assembly of Xylanase Substrates and Inhibitors

An exo-β-xylosidase mutant with glycosynthase activity was created to aid in the synthesis of xylanase substrates and inhibitors. Simple monosaccharides were easily elaborated into di-, tri- and tetrasaccharides by using this enzyme. Some products proved

Biocatalytic preparation of enantioenriched 3,4-dihydroxypiperidines and theoretical study of Candida antarctica lipase B enantioselectivity

Enzymatic acetylations of N-substituted cis- and trans-3,4- dihydroxypiperidine and hydrolysis of their diacetylated derivatives have been studied. High enantioselectivities are obtained with Pseudomonas cepacia lipase and Candida antarctica lipase B for