124817-91-0

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 767-00-0 4-cyanophenol 
• 109431-87-0 (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate 

Downstream Products

• 124731-71-1 (+)-N-<1-benzoyl-cis-3-(4-cyanophenoxy)-D-prolyl>-L-isoleucine methyl ester 
• 124817-94-3 4-((S)-1-Chloro-pyrrolidin-3-yloxy)-benzonitrile 
• 123043-40-3 (3S)-(4-cyanophenoxy)-4,5-dihydropyrrole 
• 124817-93-2 (3S)-3-(4-cyanophenoxy)pyrrolidinium trifluoroacetate 

Relevant academic research and scientific papers

NOVEL OXADIAZOLES

The present invention relates to novel compound of Formula I, wherein, R1, A1, A2, A3, A4, A5, L1, A, L2 and R2 are as defined in the detailed description. The present invention also relates to a combination or a composition comprising the compound of Formula I.

Model studies directed toward the total synthesis of 14-membered cyclopeptide alkaloids: Synthesis of prolyl peptides via a four-component condensation

The general applicability of a four-component condensation for the formation of N-acyl-β-aryloxyprolines has been demonstrated in several model studies. The relative stereochemistry of the diastereoisomers obtained has been assigned from 1H n.m.r. studies, and confirmed by an X-ray analysis of one of the stereoisomers.