124840-72-8Relevant academic research and scientific papers
Total synthesis of dispyrin, purpurealidin E, and aplysamine-1
Yoshida, Makoto,Yamaguchi, Kentaro
scheme or table, p. 1362 - 1363 (2009/09/06)
Bromotyrosine alkaloids dispyrin (1), purpurealidin E (2), and aplysamine-1 (3) isolated from marine sponge, were synthesized from commercially available tyramine (4) as a common starting material. The overall yield was 18%, 39%, and 22% for 1 from 4 in 5
On the Synthesis of Tiliacora Alkaloids, I: Synthesis of The Ansymmetrical Dibenzo-1,4-dioxin-Derivative
Pachaly, Peter,Schaefer, Michael
, p. 477 - 482 (2007/10/02)
The N-protected phenylethylamines 2 and 3, respectively, were synthesized in six steps, starting from 2a and 3a.The mixed double Ullmann reaction of 2 with 3 leads to the asymmetrical dibenzo-1,4-dioxin derivative K.On account of the selectively removable protective groups for the amino functions, K is a proper intermediate for the constitution-selective synthesis of the tiliacora alkaloids 1a - 1d.
